COVID vaccine could affect menstruation, but not fertility

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Vaccines against COVID-19 may slightly and temporarily alter the menstrual cycle, but do not affect pregnancy rates in women undergoing in vitro fertilization (IVF), new studies confirm.

Many women have reported that after receiving the COVID-19 vaccine they had irregular periods in their periods, causing them to worry that these changes could have an effect on their fertility. Several studies have investigated the effect of these drugs on menstruation and the ability to conceive in women, and their results show that vaccination can slightly alter menstruation, but vaccination does not endanger fertility or the onset of pregnancy.

A few weeks ago we already reported that they had discovered that the COVID-19 vaccine could increase the length of the menstrual cycle by one day. Now, another study published in the British Medical Journal (BMJ) has indicated that although changes have been observed in women’s menstruation, these are insignificant and short-lived.

Specifically, it was found that the 2,403 participants who were vaccinated had a menstruation delay of 0.45 days after the second dose of the COVID vaccine. This figure increased to 2.32 days in 358 women who had received both doses of the vaccine schedule during the same menstrual cycle. Victoria Male, author of this research, has highlighted that these changes returned to normal after two menstrual cycles after administration of the vaccine.

The changes in menstruation were more significant when the two doses were received in the same cycle, but the effects disappeared after two menstrual cycles

The investigation also took into account another study carried out in Norway and in which 5,688 vaccinated women participated. The findings showed that 38% of them had at least one menstrual change – such as unexpected bleeding or more severe pain – after vaccination, 39% after the first dose, and 41% after the second.

“These results are reassuring. Yes, there are changes in the menstrual cycle after vaccination, but these are minor when compared to natural variations and are quickly reversed, ”Victoria Male clarified.

The COVID vaccine does not alter fertility or the start of pregnancy

Other work published in Obstetrics & Gynecology has indicated that the SARS-CoV-2 vaccine does not affect fertility outcomes in patients who had undergone in vitro fertilization (IVF). These results were obtained after analyzing rates of fertilization, pregnancy and premature abortion in IVF patients who had received two doses of the Pfizer or Moderna mRNA vaccines, and compared them with those of the unvaccinated.

“These findings show absolutely no difference between vaccinated and unvaccinated patients in ovarian stimulation, egg quality, embryo development, pregnancy rates, and premature abortions,” said Christopher M. Zahn, of the American College of Obstetricians and Gynecologists (ACOG).

In addition, they emphasize that these results should reassure all those women who are trying to get pregnant or who are at the beginning of pregnancy. However, these analyzes have been carried out only with the complete regimen and do not include the potential effects of booster vaccines, which must be further investigated.

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