How stress and insomnia in menopause affect heart health

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Women who experience stressful life situations or do not sleep well during menopause are at increased risk of developing atrial fibrillation (irregular heart rhythms) and other cardiovascular problems.

Atrial fibrillation primarily affects older adults, is characterized by irregular heart rhythms, and can have serious health consequences such as blood clots, strokes, heart failure, and other cardiovascular complications.

A new investigation has revealed that one in four women can develop atrial fibrillation after menopause and that the main risk factors that influence its appearance are stress and insomnia, which highlights the importance of taking care of emotional well-being and rest during this stage of life.

“In my general cardiology practice, I see many postmenopausal women in perfect physical health who struggle with lack of sleep and negative psychological and emotional feelings or experiences, which we now know can put them at risk of developing atrial fibrillation,” said Dr. Dr. Susan. X. Zhao, a cardiologist at Santa Clara Valley Medical Center in San Jose, Calif., and the study’s lead author. “I strongly believe that, in addition to age, genetics and other risk factors related to heart health, psychosocial factors are the missing piece in the puzzle of the genesis of atrial fibrillation.”

Lack of sleep can increase the risk of atrial fibrillation

The research analyzed data from 83,736 women between the ages of 50 and 79 (with an average age of 64 years) who responded to questionnaires for the Women’s Health Initiative, a major US study. Participants were asked questions about stressful life events—loss of a loved one, illness, divorce, financial problems, and verbal, physical, or sexual domestic abuse—feeling of optimism—believing that good things can happen—social support –having friends to talk to in difficult or stressful situations, having help with daily tasks…– and insomnia –problems falling asleep, waking up during the night and general quality of sleep–.

“Atrial fibrillation is a disease of the electrical conduction system and is prone to hormonal changes resulting from stress and lack of sleep”

The researchers found that stressful life situations, lack of sleep, disorders such as depression or anxiety, or feelings of being overwhelmed by one’s circumstances are often interrelated. It is difficult to know if these factors progressively accumulate over the years to increase the risk of atrial fibrillation as women age.

During the 10 years of follow-up, 23,954 women (25%) developed atrial fibrillation. The results of the study have been published in the Journal of the American Heart Association, a journal of the American Heart Association, and show that for each additional point on the insomnia scale there is a 4% greater chance of developing atrial fibrillation, and for each additional point on the scale of stressful life events there is a 2% higher probability of suffering from atrial fibrillation.
“The connection between the heart and the brain has been established for a long time in many conditions,” Zhao says. “Atrial fibrillation is a disease of the electrical conduction system and is prone to hormonal changes resulting from stress and lack of sleep. These common pathways likely underpin the association between stress and insomnia with atrial fibrillation.”
Chronic stress has not been consistently associated with atrial fibrillation, and the researchers note that one limitation of their study is that it relied on patient questionnaires used at baseline during stressful life events, however significant. and traumatic, may not be long-lasting, Zhao cautions, so further research is needed to confirm these associations and determine whether personalized stress-relieving interventions can modify the risk of atrial fibrillation.
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